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Oncologist in Kolkata
Reviewed by

Dr. Subrata Saha

Consultant - Medical Oncology

Manipal Hospitals, Salt Lake

Vaginal Cancer: Symptoms And Causes

Reviewed by:

Dr. Subrata Saha

Posted On: Oct 03, 2023

blogs read 6 Min Read

Vaginal Cancer Treatment and Causes

Vaginal cancer is a rare form of cancer that develops in the muscle tube connecting the uterus to the outer genitalia, or vagina. The vagina, also known as the birth canal, is lined with cells, and these cells are where vaginal cancer most frequently develops. The likelihood of a cure is highest when vaginal cancer is discovered in its early stages. The treatment for vaginal cancer that has spread outside of the vagina is substantially more challenging. We will discuss vaginal cancer treatment and causes in this blog and all it's challenges.

Diagnosis and Treatment

The following tests and procedures are used for the diagnosis of vaginal cancer:

  • Pelvic exam

The healthcare professional will visually examine the vulva and feel for any anomalies by inserting two fingers within the vagina. The vagina is spacious. Sometimes the two walls can be temporarily gently separated using a device known as a speculum, making it simpler to see the cervix and vaginal canal.

  • Pap Smear

The healthcare professional will scrape cells from the cervix while holding the vagina open with a speculum and a spatula-like tool. For indications of malignancy or HPV, these cells will be examined in a lab. It takes a few seconds to take smear. 

  • Colposcopy

The doctor will examine the vagina and cervix using lighted equipment called a colposcope or vaginoscope to check for abnormal cells.

  • Biopsy

It is frequently performed by colposcopy. In order to check for cancer cells, the healthcare professional will collect a pinch of tissue sample. With friendly advanced local anaesthesia, it is painless. The treatment is determined by the type of cancer, the stage of the cancer, and the patient's age. Precancerous cells are typically treated with removal, laser surgery and topical therapies. Surgery, radiation, and chemotherapy are frequently needed to treat invasive vaginal cancer. There are several therapies that you might get.

  • Surgery

    • Wide local excision

The tumour and some of the surrounding healthy tissue are removed.

  • Vaginectomy (Partial or Radical)

Depending on the size and location of the tumour, the doctor may remove all or some parts of the vagina. The doctor may advise having the lymph nodes, uterus, and cervix removed (lymph node dissection), depending on how far the cancer has spread (hysterectomy). 

  • Pelvic Exenteration

This is needed in advanced cases. This procedure removes several organs, including the bladder, uterus, cervix, vagina, ovaries, and adjacent lymph nodes from the pelvis. The gynaecologic oncologists in saltlake, Kolkata will create an opening in the abdomen for urination and bowel movement (called a stoma or ostomy bag). This surgery is recommended if someone has cancer that keeps coming back.

  • Radiation Therapy

Radiation kills cancer cells or prevents them from proliferating by using focused energy beams, like X-rays.

  • External Radiation Therapy

High-energy radiation beams are focused on the tumour by an external machine.

  • Internal Radiation Therapy

Radioactive materials are inserted into or close to the tumour in the vagina using catheters or sealed wires. These give short doses of radiation and are removed after each dose. 

  • Chemotherapy

In this, cancer cells are killed using medications.

  • Clinical Trials

World is advancing quick to find novel cancer treatment. Without the help of patients this cannot be achieved. The doctor might offer the patient to enrol in a clinical study to check out innovative cancer treatments.

Types of Vaginal Cancer

Vaginal cancer comes in various forms. The following are the common vaginal cancers:

  • Squamous Cell Carcinoma

The flat cells, or squamous cells, that line the vagina are where squamous cell cancer originates. The most typical kind of vaginal cancer issquamous cell carcinoma. It represents around 90% of all instances.

  • Adenocarcinoma

This type of vaginal cancer is found originally in the gland cells of the vagina and commonly affects the younger age group. There is a special variety of vaginal cancer, clear-cell adenocarcinoma. This happens in women who were exposed to a medication diethylstilbestrol (DES) while they were still within their mother’s womb. Paradoxically, this was a medicine used to treat miscarriages till late 1970s. Now it is banned.

  • Melanoma

It usually starts within the cells that provide colour to the skin neighbouring vagina (melanocytes). Vaginal melanomas are very rare.

  • Sarcoma

It develops within the connective tissue and muscle tissue that make up the vaginal wall. Vaginal sarcomas are uncommon, just as are vaginal melanomas. Sarcomas come in a variety of forms. The most frequent type is rhabdomyosarcoma, which primarily affects children. While leiomyosarcoma is a disease of middle-aged women.

Who Develops Vaginal Cancer?

The risk of developing vaginal cancer rises if:

  • The woman is over 60 years old.
  • If the women develops persistent human papillomavirus (HPV). These infections does not give symptoms. 
  • The individual is diagnosed with vaginal intraepithelial neoplasia (VAIN).
  • The individual has experienced cervical dysplasia or malignancy.
  • Women who came into contact with diethylstilbestrol (DES).
  • Women with smoking habits.

Symptoms of Vaginal Cancer

Early vaginal cancer may not show any symptoms at all. Vaginal cancer may manifest as the following signs and symptoms as it progresses:

  • Unusual bleeding from the vagina.
  • Watery or unpleasant vaginal discharge.
  • Pain in the pelvis.
  • Pain during sexual activity.
  • Difficulty in urinating.
  • Feeling the need to urinate while having an empty stomach.
  • More urination than usual.
  • Constipation.
  • A lump in the vagina.

How Common is Vaginal Cancer?

True vaginal cancers are rare. Vaginal cancer makes up about 2-3% of all gynaecological cancers. Vagina is commonly affected with cancer from other neighbouring organs. These are not primary vaginal cancers.

Cause Of Vaginal Cancer

What specifically causes vaginal cancer is unknown to researchers. Vaginal cancer and high-risk HPV strains are likely linked, just as they are with cervical cancer. It is considered HPV vaccines will also protect against vaginal cancers.

Transmission Of Vaginal Cancer

Cancer cells in the vagina behave like all cancer cells. As the cells grow uncontrollably, tumours develop. These tumours may invade adjacent healthy tissue and metastasise (spread to other body parts).

FAQ's

Breast lumps may occur as a result of unchecked cell proliferation, which is the first sign of breast cancer. It is one of the cancer types that is curable. It can also spread to other body parts, making it a potentially fatal disease if not diagnosed on time. Women worldwide, both in developed and developing nations, are affected by breast cancer. Although it can happen at any age, women over the age of 40 are the ones most likely to experience it. 25%-31% of all malignancies in women in India are breast cancers. The average age at which breast cancer develops has also changed significantly, going from 50-70 to 30-50.

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